‘Tangles’ & Alzheimer’s Disease: Release Date, Cast & How to Watch – Hollywood Life

An animation is typically categorized with other children’s flicks. Take a Pixar project or a clay-mation, which has resurfaced this year with Wildwood. Not many animated films are produced for a mostly-adult audience; nor do most center on a difficult medical subject — and that’s where Tangles comes into the conversation. Featuring an all-star cast packed with Julia Louis-Dreyfus, Abbi Jacobson, Bryan Cranston, Beanie Feldstein, Seth Rogen and several more, the 2026 movie hits theaters in January next year and follows a daughter who returns home to help care for her once-vibrant mother amid her decline from Alzheimer’s disease.

Hollywood Life caught up with some of the cast at the New York City red carpet and screening, where film, TV and Broadway multi-hyphenate Cranston emphasized that the film focuses not only on the person living with dementia, but also the family struggling alongside their sweet matriarch throughout her journey.

“The world needs empathy” the Breaking Bad alum said. When asked if he considers empathy a “lifeline” for society, Cranston replied affirmatively and briefly recalled his late mother’s battle with Alzheimer’s disease.

Hollywood Life is breaking down what you need to know about Tangles — written by Sarah Leavitt, based on her graphic novel, and directed by Leah Nelson — from its release date to exclusive details from the all-star cast.

What Is Tangles About?

Per its official synopsis, Tangles follows Sarah (Jacobson), who “finds love and independence in 1990s San Francisco” while “a visit home reunites her with her vibrant mother Midge (Louis-Dreyfus) and the wonderfully imperfect family that shaped her.”

“When Midge is diagnosed with Alzheimer’s, Sarah discovers that while family is never simple, the ties that bind us — through laughter, heartbreak and joy — endure even as memories begin to fade,” the rest of the synopsis reads.

Who Is in the Tangles Cast?

As previously noted, Tangles is packed with quite a few of Hollywood’s most respected names. In addition to Cranston, Rogen, Feldstein and Louis-Dreyfus, the rest of the cast features Samira Wiley, Sarah Silverman, Wanda Sykes, Bowen Yang, Pamela Adlon and Fern Grandin.

How Can You Watch Tangles?

True moviegoers already know that they need to enjoy a film on the big screen. So, Tangles will be released in limited theaters in the U.S. on January 15, 2027, and will subsequently have a wider theatrical release on January 22.